Role of Pfmdr1 in In Vitro Plasmodium falciparum Susceptibility to Chloroquine, Quinine, Monodesethylamodiaquine, Mefloquine, Lumefantrine, and Dihydroartemisinin

The involvement of Pfmdr1 (Plasmodium falciparum multidrug resistance 1) polymorphisms in antimalarial drug resistance is still debated. Here, we evaluate the association between polymorphisms in Pfmdr1 (N86Y, Y184F, S1034C, N1042D, and D1246Y) and Pfcrt (K76T) and in vitro responses to chloroquine...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Wurtz, Nathalie, Fall, Bécaye, Pascual, Aurélie, Fall, Mansour, Baret, Eric, Camara, Cheikhou, Nakoulima, Aminata, Diatta, Bakary, Fall, Khadidiatou Ba, Mbaye, Pape Saliou, Diémé, Yaya, Bercion, Raymond, Wade, Boubacar, Pradines, Bruno
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Mechanisms of Resistance
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249527/
https://ncbi.nlm.nih.gov/pubmed/25199781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03494-14
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