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The 6-Aminoquinolone WC5 Inhibits Different Functions of the Immediate-Early 2 (IE2) Protein of Human Cytomegalovirus That Are Essential for Viral Replication

The human cytomegalovirus (HCMV) immediate-early 2 (IE2) protein is a multifunctional factor essential for viral replication. IE2 modulates both viral and host gene expression, deregulates cell cycle progression, acts as an immunomodulator, and antagonizes cellular antiviral responses. Based on thes...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Antimicrob Agents Chemother
Κύριοι συγγραφείς: Mercorelli, Beatrice, Luganini, Anna, Muratore, Giulia, Massari, Serena, Terlizzi, Maria Elena, Tabarrini, Oriana, Gribaudo, Giorgio, Palù, Giorgio, Loregian, Arianna
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249379/
https://ncbi.nlm.nih.gov/pubmed/25155603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03309-14
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