A 6-Aminoquinolone Compound, WC5, with Potent and Selective Anti-Human Cytomegalovirus Activity

We identified a 6-aminoquinolone compound, WC5, that inhibits human cytomegalovirus (HCMV) replication with a selectivity index of ∼500. WC5 also showed activity against drug-resistant HCMV strains. In contrast, it did not significantly affect the replication of human herpesvirus 6 and 8 and was ∼10...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Mercorelli, Beatrice, Muratore, Giulia, Sinigalia, Elisa, Tabarrini, Oriana, Biasolo, Maria Angela, Cecchetti, Violetta, Palù, Giorgio, Loregian, Arianna
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2009
נושאים:
Antiviral Agents
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612181/
https://ncbi.nlm.nih.gov/pubmed/19015358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00988-08
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים