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Human Cytomegalovirus Inhibitor AL18 Also Possesses Activity against Influenza A and B Viruses

AL18, an inhibitor of human cytomegalovirus DNA polymerase, was serendipitously found to also block the interaction between the PB1 and PA polymerase subunits of influenza A virus. Furthermore, AL18 effectively inhibited influenza A virus polymerase activity and the overall replication of influenza...

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Detalhes bibliográficos
Main Authors: Muratore, Giulia, Mercorelli, Beatrice, Goracci, Laura, Cruciani, Gabriele, Digard, Paul, Palù, Giorgio, Loregian, Arianna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3486565/
https://ncbi.nlm.nih.gov/pubmed/22908168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01219-12
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