BCX4430, a Novel Nucleoside Analog, Effectively Treats Yellow Fever in a Hamster Model

No effective antiviral therapies are currently available to treat disease after infection with yellow fever virus (YFV). A Syrian golden hamster model of yellow fever (YF) was used to characterize the effect of treatment with BCX4430, a novel adenosine nucleoside analog. Significant improvement in s...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Julander, Justin G., Bantia, Shanta, Taubenheim, Brian R., Minning, Dena M., Kotian, Pravin, Morrey, John D., Smee, Donald F., Sheridan, William P., Babu, Yarlagadda S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249364/
https://ncbi.nlm.nih.gov/pubmed/25155605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03368-14
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