Mycobacterium tuberculosis Strains Lacking Surface Lipid Phthiocerol Dimycocerosate Are Susceptible to Killing by an Early Innate Host Response

The innate immune response plays an important but unknown role in host defense against Mycobacterium tuberculosis. To define the function of innate immunity during tuberculosis, we evaluated M. tuberculosis replication dynamics during murine infection. Our data show that the early pulmonary innate i...

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Bibliografske podrobnosti
izdano v:Infect Immun
Main Authors: Day, Tracey A., Mittler, John E., Nixon, Molly R., Thompson, Cullen, Miner, Maurine D., Hickey, Mark J., Liao, Reiling P., Pang, Jennifer M., Shayakhmetov, Dmitry M., Sherman, David R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Bacterial Infections
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249296/
https://ncbi.nlm.nih.gov/pubmed/25287926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01340-13
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