Mycobacterium tuberculosis Strains Lacking Surface Lipid Phthiocerol Dimycocerosate Are Susceptible to Killing by an Early Innate Host Response

The innate immune response plays an important but unknown role in host defense against Mycobacterium tuberculosis. To define the function of innate immunity during tuberculosis, we evaluated M. tuberculosis replication dynamics during murine infection. Our data show that the early pulmonary innate i...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Day, Tracey A., Mittler, John E., Nixon, Molly R., Thompson, Cullen, Miner, Maurine D., Hickey, Mark J., Liao, Reiling P., Pang, Jennifer M., Shayakhmetov, Dmitry M., Sherman, David R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
Assuntos:
Bacterial Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249296/
https://ncbi.nlm.nih.gov/pubmed/25287926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01340-13
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