Mycobacterium tuberculosis Strains Lacking Surface Lipid Phthiocerol Dimycocerosate Are Susceptible to Killing by an Early Innate Host Response

The innate immune response plays an important but unknown role in host defense against Mycobacterium tuberculosis. To define the function of innate immunity during tuberculosis, we evaluated M. tuberculosis replication dynamics during murine infection. Our data show that the early pulmonary innate i...

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Gepubliceerd in:Infect Immun
Hoofdauteurs: Day, Tracey A., Mittler, John E., Nixon, Molly R., Thompson, Cullen, Miner, Maurine D., Hickey, Mark J., Liao, Reiling P., Pang, Jennifer M., Shayakhmetov, Dmitry M., Sherman, David R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2014
Onderwerpen:
Bacterial Infections
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249296/
https://ncbi.nlm.nih.gov/pubmed/25287926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01340-13
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