Mycobacterium tuberculosis Strains Lacking Surface Lipid Phthiocerol Dimycocerosate Are Susceptible to Killing by an Early Innate Host Response

The innate immune response plays an important but unknown role in host defense against Mycobacterium tuberculosis. To define the function of innate immunity during tuberculosis, we evaluated M. tuberculosis replication dynamics during murine infection. Our data show that the early pulmonary innate i...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Day, Tracey A., Mittler, John E., Nixon, Molly R., Thompson, Cullen, Miner, Maurine D., Hickey, Mark J., Liao, Reiling P., Pang, Jennifer M., Shayakhmetov, Dmitry M., Sherman, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249296/
https://ncbi.nlm.nih.gov/pubmed/25287926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01340-13
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