Mycobacterium tuberculosis Strains Lacking Surface Lipid Phthiocerol Dimycocerosate Are Susceptible to Killing by an Early Innate Host Response

The innate immune response plays an important but unknown role in host defense against Mycobacterium tuberculosis. To define the function of innate immunity during tuberculosis, we evaluated M. tuberculosis replication dynamics during murine infection. Our data show that the early pulmonary innate i...

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Vydáno v:Infect Immun
Hlavní autoři: Day, Tracey A., Mittler, John E., Nixon, Molly R., Thompson, Cullen, Miner, Maurine D., Hickey, Mark J., Liao, Reiling P., Pang, Jennifer M., Shayakhmetov, Dmitry M., Sherman, David R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Bacterial Infections
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249296/
https://ncbi.nlm.nih.gov/pubmed/25287926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01340-13
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