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The 2′-5′-Oligoadenylate Synthetase 3 Enzyme Potently Synthesizes the 2′-5′-Oligoadenylates Required for RNase L Activation

The members of the oligoadenylate synthetase (OAS) family of proteins are antiviral restriction factors that target a wide range of RNA and DNA viruses. They function as intracellular double-stranded RNA (dsRNA) sensors that, upon binding to dsRNA, undergo a conformational change and are activated t...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Ibsen, Mikkel Søes, Gad, Hans Henrik, Thavachelvam, Karthiga, Boesen, Thomas, Desprès, Philippe, Hartmann, Rune
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249133/
https://ncbi.nlm.nih.gov/pubmed/25275129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01763-14
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