HIV Control Is Mediated in Part by CD8(+) T-Cell Targeting of Specific Epitopes

We investigated the hypothesis that the correlation between the class I HLA types of an individual and whether that individual spontaneously controls HIV-1 is mediated by the targeting of specific epitopes by CD8(+) T cells. By measuring gamma interferon enzyme-linked immunosorbent spot (ELISPOT) as...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Pereyra, Florencia, Heckerman, David, Carlson, Jonathan M., Kadie, Carl, Soghoian, Damien Z., Karel, Daniel, Goldenthal, Ariel, Davis, Oliver B., DeZiel, Charles E., Lin, Tienho, Peng, Jian, Piechocka, Alicja, Carrington, Mary, Walker, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249072/
https://ncbi.nlm.nih.gov/pubmed/25165115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01004-14
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