Ligand-Independent Exhaustion of Killer Immunoglobulin-Like Receptor-Positive CD8(+) T Cells in Human Immunodeficiency Virus Type 1 Infection

Virus-specific CD8(+) T cells play a central role in the control of viral infections, including human immunodeficiency virus type 1 (HIV-1) infection. However, despite the presence of strong and broad HIV-specific CD8(+) T-cell responses in chronic HIV-1 infection, these cells progressively lose cri...

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Detalhes bibliográficos
Main Authors: Alter, Galit, Rihn, Suzannah, Streeck, Hendrik, Teigen, Nickolas, Piechocka-Trocha, Alicja, Moss, Kristin, Cohen, Kristen, Meier, Angela, Pereyra, Florencia, Walker, Bruce, Altfeld, Marcus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546972/
https://ncbi.nlm.nih.gov/pubmed/18579582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00341-08
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