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IL-10 induces aberrant deletion of dendritic cells by natural killer cells in the context of HIV infection

Persistent levels of IL-10 play a central role in progressive immune dysfunction associated with chronic viral infections such as HIV, but the underlying mechanisms are poorly understood. Because IL-10 affects the phenotypic and functional properties of DCs, which are responsible for initiating adap...

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Detalhes bibliográficos
Main Authors: Alter, Galit, Kavanagh, Daniel, Rihn, Suzannah, Luteijn, Rutger, Brooks, David, Oldstone, Michael, van Lunzen, Jan, Altfeld, Marcus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877944/
https://ncbi.nlm.nih.gov/pubmed/20440075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40913
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