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Analysis of the Evolution and Structure of a Complex Intrahost Viral Population in Chronic Hepatitis C Virus Mapped by Ultradeep Pyrosequencing

Hepatitis C virus (HCV) causes chronic infection in up to 50% to 80% of infected individuals. Hypervariable region 1 (HVR1) variability is frequently studied to gain an insight into the mechanisms of HCV adaptation during chronic infection, but the changes to and persistence of HCV subpopulations du...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Palmer, Brendan A., Dimitrova, Zoya, Skums, Pavel, Crosbie, Orla, Kenny-Walsh, Elizabeth, Fanning, Liam J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248971/
https://ncbi.nlm.nih.gov/pubmed/25231312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01732-14
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