Whole-Genome Characterization of Human and Simian Immunodeficiency Virus Intrahost Diversity by Ultradeep Pyrosequencing

Rapid evolution and high intrahost sequence diversity are hallmarks of human and simian immunodeficiency virus (HIV/SIV) infection. Minor viral variants have important implications for drug resistance, receptor tropism, and immune evasion. Here, we used ultradeep pyrosequencing to sequence complete...

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Hlavní autoři: Bimber, Benjamin N., Dudley, Dawn M., Lauck, Michael, Becker, Ericka A., Chin, Emily N., Lank, Simon M., Grunenwald, Haiying L., Caruccio, Nicholas C., Maffitt, Mark, Wilson, Nancy A., Reed, Jason S., Sosman, James M., Tarosso, Leandro F., Sanabani, Sabri, Kallas, Esper G., Hughes, Austin L., O'Connor, David H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Genetic Diversity and Evolution
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2977871/
https://ncbi.nlm.nih.gov/pubmed/20844037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01378-10
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