Whole-Genome Characterization of Human and Simian Immunodeficiency Virus Intrahost Diversity by Ultradeep Pyrosequencing

Rapid evolution and high intrahost sequence diversity are hallmarks of human and simian immunodeficiency virus (HIV/SIV) infection. Minor viral variants have important implications for drug resistance, receptor tropism, and immune evasion. Here, we used ultradeep pyrosequencing to sequence complete...

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Detalhes bibliográficos
Main Authors: Bimber, Benjamin N., Dudley, Dawn M., Lauck, Michael, Becker, Ericka A., Chin, Emily N., Lank, Simon M., Grunenwald, Haiying L., Caruccio, Nicholas C., Maffitt, Mark, Wilson, Nancy A., Reed, Jason S., Sosman, James M., Tarosso, Leandro F., Sanabani, Sabri, Kallas, Esper G., Hughes, Austin L., O'Connor, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Genetic Diversity and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2977871/
https://ncbi.nlm.nih.gov/pubmed/20844037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01378-10
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