Whole-Genome Characterization of Human and Simian Immunodeficiency Virus Intrahost Diversity by Ultradeep Pyrosequencing

Rapid evolution and high intrahost sequence diversity are hallmarks of human and simian immunodeficiency virus (HIV/SIV) infection. Minor viral variants have important implications for drug resistance, receptor tropism, and immune evasion. Here, we used ultradeep pyrosequencing to sequence complete...

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Bibliografische gegevens
Hoofdauteurs: Bimber, Benjamin N., Dudley, Dawn M., Lauck, Michael, Becker, Ericka A., Chin, Emily N., Lank, Simon M., Grunenwald, Haiying L., Caruccio, Nicholas C., Maffitt, Mark, Wilson, Nancy A., Reed, Jason S., Sosman, James M., Tarosso, Leandro F., Sanabani, Sabri, Kallas, Esper G., Hughes, Austin L., O'Connor, David H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2010
Onderwerpen:
Genetic Diversity and Evolution
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2977871/
https://ncbi.nlm.nih.gov/pubmed/20844037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01378-10
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