Whole-Genome Characterization of Human and Simian Immunodeficiency Virus Intrahost Diversity by Ultradeep Pyrosequencing

Rapid evolution and high intrahost sequence diversity are hallmarks of human and simian immunodeficiency virus (HIV/SIV) infection. Minor viral variants have important implications for drug resistance, receptor tropism, and immune evasion. Here, we used ultradeep pyrosequencing to sequence complete...

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書誌詳細
主要な著者: Bimber, Benjamin N., Dudley, Dawn M., Lauck, Michael, Becker, Ericka A., Chin, Emily N., Lank, Simon M., Grunenwald, Haiying L., Caruccio, Nicholas C., Maffitt, Mark, Wilson, Nancy A., Reed, Jason S., Sosman, James M., Tarosso, Leandro F., Sanabani, Sabri, Kallas, Esper G., Hughes, Austin L., O'Connor, David H.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2010
主題:
Genetic Diversity and Evolution
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2977871/
https://ncbi.nlm.nih.gov/pubmed/20844037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01378-10
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