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Molecular Basis for Ebolavirus VP35 Suppression of Human Dendritic Cell Maturation
Zaire ebolavirus (EBOV) VP35 is a double-stranded RNA (dsRNA)-binding protein that inhibits RIG-I signaling and alpha/beta interferon (IFN-α/β) responses by both dsRNA-binding-dependent and -independent mechanisms. VP35 also suppresses dendritic cell (DC) maturation. Here, we define the pathways and...
Enregistré dans:
| Publié dans: | J Virol |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4248944/ https://ncbi.nlm.nih.gov/pubmed/25142601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02163-14 |
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