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Ebolavirus VP35 suppresses IFN production from conventional but not plasmacytoid dendritic cells
Ebolaviruses naturally infect a wide variety of cells including macrophages and dendritic cells, and the resulting cytokine and interferon-α/β responses of infected cells are thought to influence viral pathogenesis. The VP35 protein impairs RIG-I-like receptor dependent signaling to inhibit interfer...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4148147/ https://ncbi.nlm.nih.gov/pubmed/21263462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2010.169 |
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