VP24-Karyopherin Alpha Binding Affinities Differ between Ebolavirus Species, Influencing Interferon Inhibition and VP24 Stability

Zaire ebolavirus (EBOV), Bundibugyo ebolavirus (BDBV), and Reston ebolavirus (RESTV) belong to the same genus but exhibit different virulence properties. VP24 protein, a structural protein present in all family members, blocks interferon (IFN) signaling and likely contributes to virulence. Inhibitio...

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Schwarz, Toni M., Edwards, Megan R., Diederichs, Audrey, Alinger, Joshua B., Leung, Daisy W., Amarasinghe, Gaya K., Basler, Christopher F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2017
Aiheet:
Virus-Cell Interactions
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286879/
https://ncbi.nlm.nih.gov/pubmed/27974555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01715-16
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