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Kinetic and Phenotypic Analysis of CD8(+) T Cell Responses after Priming with Alphavirus Replicons and Homologous or Heterologous Booster Immunizations

Alphavirus replicons are potent inducers of CD8(+) T cell responses and thus constitute an attractive vaccine vector platform for developing novel vaccines. However, the kinetics and memory phenotype of CD8(+) T cell responses induced by alphavirus replicons are not well characterized. Furthermore,...

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Publicado en:J Virol
Autores principales: Knudsen, Maria Lisa, Ljungberg, Karl, Kakoulidou, Maria, Kostic, Linda, Hallengärd, David, García-Arriaza, Juan, Merits, Andres, Esteban, Mariano, Liljeström, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248943/
https://ncbi.nlm.nih.gov/pubmed/25122792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02223-14
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