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Visualization of Retroviral Envelope Spikes in Complex with the V3 Loop Antibody 447-52D on Intact Viruses by Cryo-Electron Tomography

The gp120 portion of the envelope spike on human immunodeficiency virus type 1 (HIV-1) plays a critical role in viral entry into host cells and is a key target for the humoral immune response, and yet many structural details remain elusive. We have used cryoelectron tomography to visualize the bindi...

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Vydáno v:J Virol
Hlavní autoři: Dutta, Moumita, Liu, Jun, Roux, Kenneth H., Taylor, Kenneth A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248906/
https://ncbi.nlm.nih.gov/pubmed/25122783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01596-14
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