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Structural Comparison of HIV-1 Envelope Spikes with and without the V1/V2 Loop

We have used cryoelectron tomography of vitreous-ice-embedded HIV-1 virions to compare the envelope (Env) spikes of a wild-type strain with those of a mutant strain in which the V1/V2 loop has been deleted. Deletion of V1/V2 results in a spike with far more structural heterogeneity than is observed...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Hu, Guiqing, Liu, Jun, Taylor, Kenneth A., Roux, Kenneth H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067966/
https://ncbi.nlm.nih.gov/pubmed/21191026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01612-10
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