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Structural Comparison of HIV-1 Envelope Spikes with and without the V1/V2 Loop
We have used cryoelectron tomography of vitreous-ice-embedded HIV-1 virions to compare the envelope (Env) spikes of a wild-type strain with those of a mutant strain in which the V1/V2 loop has been deleted. Deletion of V1/V2 results in a spike with far more structural heterogeneity than is observed...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3067966/ https://ncbi.nlm.nih.gov/pubmed/21191026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01612-10 |
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