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Alteration of NCoR Corepressor Splicing in Mice Causes Increased Body Weight and Hepatosteatosis without Glucose Intolerance

Alternative mRNA splicing is an important means of diversifying function in higher eukaryotes. Notably, both NCoR and SMRT corepressors are subject to alternative mRNA splicing, yielding a series of distinct corepressor variants with highly divergent functions. Normal adipogenesis is associated with...

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Publicado en:Mol Cell Biol
Main Authors: Goodson, Michael L., Young, Briana M., Snyder, Chelsea A., Schroeder, Amy C., Privalsky, Martin L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248719/
https://ncbi.nlm.nih.gov/pubmed/25182530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00554-14
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