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Alteration of NCoR Corepressor Splicing in Mice Causes Increased Body Weight and Hepatosteatosis without Glucose Intolerance

Alternative mRNA splicing is an important means of diversifying function in higher eukaryotes. Notably, both NCoR and SMRT corepressors are subject to alternative mRNA splicing, yielding a series of distinct corepressor variants with highly divergent functions. Normal adipogenesis is associated with...

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Publié dans:Mol Cell Biol
Auteurs principaux: Goodson, Michael L., Young, Briana M., Snyder, Chelsea A., Schroeder, Amy C., Privalsky, Martin L.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248719/
https://ncbi.nlm.nih.gov/pubmed/25182530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00554-14
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