Alteration of NCoR Corepressor Splicing in Mice Causes Increased Body Weight and Hepatosteatosis without Glucose Intolerance

Alternative mRNA splicing is an important means of diversifying function in higher eukaryotes. Notably, both NCoR and SMRT corepressors are subject to alternative mRNA splicing, yielding a series of distinct corepressor variants with highly divergent functions. Normal adipogenesis is associated with...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Goodson, Michael L., Young, Briana M., Snyder, Chelsea A., Schroeder, Amy C., Privalsky, Martin L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248719/
https://ncbi.nlm.nih.gov/pubmed/25182530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00554-14
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