MicroRNAs 206 and 21 Cooperate To Promote RAS–Extracellular Signal-Regulated Kinase Signaling by Suppressing the Translation of RASA1 and SPRED1

Despite the low prevalence of activating point mutation of RAS or RAF genes, the RAS–extracellular signal-regulated kinase (ERK) pathway is implicated in breast cancer pathogenesis. Indeed, in triple-negative breast cancer (TNBC), there is recurrent genetic alteration of pathway components. Using sh...

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Bibliografische gegevens
Gepubliceerd in:Mol Cell Biol
Hoofdauteurs: Sharma, Sriganesh B., Lin, Chen-Chung, Farrugia, Mark K., McLaughlin, Sarah L., Ellis, Emily J., Brundage, Kathleen M., Salkeni, Mohamad A., Ruppert, J. Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2014
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248710/
https://ncbi.nlm.nih.gov/pubmed/25202123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00480-14
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