TLR3 deficiency in herpes simplex encephalitis: High allelic heterogeneity and recurrence risk

OBJECTIVE: To determine the proportion of children with herpes simplex encephalitis (HSE) displaying TLR3 deficiency, the extent of TLR3 allelic heterogeneity, and the specific clinical features of TLR3 deficiency. METHODS: We determined the sequence of all exons of TLR3 in 110 of the 120 patients w...

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Publicado no:Neurology
Main Authors: Lim, Hye Kyung, Seppänen, Mikko, Hautala, Timo, Ciancanelli, Michael J., Itan, Yuval, Lafaille, Fabien G., Dell, William, Lorenzo, Lazaro, Byun, Minji, Pauwels, Elodie, Rönnelid, Ylva, Cai, Xin, Boucherit, Soraya, Jouanguy, Emmanuelle, Paetau, Anders, Lebon, Pierre, Rozenberg, Flore, Tardieu, Marc, Abel, Laurent, Yildiran, Alisan, Vergison, Anne, Roivainen, Reina, Etzioni, Amos, Tienari, Pentti J., Casanova, Jean-Laurent, Zhang, Shen-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248460/
https://ncbi.nlm.nih.gov/pubmed/25339207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000000999
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