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Novel Primary Immunodeficiency Candidate Genes Predicted by the Human Gene Connectome

Germline genetic mutations underlie various primary immunodeficiency (PID) diseases. Patients with rare PID diseases (like most non-PID patients and healthy individuals) carry, on average, 20,000 rare and common coding variants detected by high-throughput sequencing. It is thus a major challenge to...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Itan, Yuval, Casanova, Jean-Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381650/
https://ncbi.nlm.nih.gov/pubmed/25883595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00142
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