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Small-Molecule SMAC Mimetics as New Cancer Therapeutics
Apoptosis is a tightly regulated cellular process and faulty regulation of apoptosis is a hallmark of human cancers. Targeting key apoptosis regulators with the goal to restore apoptosis in tumor cells has been pursued as a new cancer therapeutic strategy. XIAP, cIAP1, and cIAP2, members of inhibito...
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| Publicado no: | Pharmacol Ther |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4247261/ https://ncbi.nlm.nih.gov/pubmed/24841289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2014.05.007 |
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