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Small-Molecule SMAC Mimetics as New Cancer Therapeutics

Apoptosis is a tightly regulated cellular process and faulty regulation of apoptosis is a hallmark of human cancers. Targeting key apoptosis regulators with the goal to restore apoptosis in tumor cells has been pursued as a new cancer therapeutic strategy. XIAP, cIAP1, and cIAP2, members of inhibito...

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Bibliografski detalji
Izdano u:Pharmacol Ther
Glavni autori: Bai, Longchuan, Smith, David C., Wang, Shaomeng
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247261/
https://ncbi.nlm.nih.gov/pubmed/24841289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2014.05.007
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