Gene expression in whole lung and pulmonary macrophages reflects the dynamic pathology associated with airway surface dehydration

BACKGROUND: Defects in airway mucosal defense, including decreased mucus clearance, contribute to the pathogenesis of human chronic obstructive pulmonary diseases. Scnn1b-Tg mice, which exhibit chronic airway surface dehydration from birth, can be used as a model to study the pathogenesis of muco-ob...

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Gepubliceerd in:BMC Genomics
Hoofdauteurs: Saini, Yogesh, Dang, Hong, Livraghi-Butrico, Alessandra, Kelly, Elizabeth J, Jones, Lisa C, O’Neal, Wanda K, Boucher, Richard C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2014
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247008/
https://ncbi.nlm.nih.gov/pubmed/25204199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-726
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