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Gene expression in whole lung and pulmonary macrophages reflects the dynamic pathology associated with airway surface dehydration
BACKGROUND: Defects in airway mucosal defense, including decreased mucus clearance, contribute to the pathogenesis of human chronic obstructive pulmonary diseases. Scnn1b-Tg mice, which exhibit chronic airway surface dehydration from birth, can be used as a model to study the pathogenesis of muco-ob...
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Publicado no: | BMC Genomics |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4247008/ https://ncbi.nlm.nih.gov/pubmed/25204199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-726 |
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