Transcription factor PREP1 induces EMT and metastasis by controlling the TGF-β–SMAD3 pathway in non-small cell lung adenocarcinoma

Pre–B-cell leukemia homeobox (Pbx)-regulating protein-1 (Prep1) is a ubiquitous homeoprotein involved in early development, genomic stability, insulin sensitivity, and hematopoiesis. Previously we have shown that Prep1 is a haploinsufficient tumor suppressor that inhibits neoplastic transformation b...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Risolino, Maurizio, Mandia, Nadia, Iavarone, Francescopaolo, Dardaei, Leila, Longobardi, Elena, Fernandez, Serena, Talotta, Francesco, Bianchi, Fabrizio, Pisati, Federica, Spaggiari, Lorenzo, Harter, Patrick N., Mittelbronn, Michel, Schulte, Dorothea, Incoronato, Mariarosaria, Di Fiore, Pier Paolo, Blasi, Francesco, Verde, Pasquale
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246949/
https://ncbi.nlm.nih.gov/pubmed/25157139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1407074111
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