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miR-340 inhibits tumor cell proliferation and induces apoptosis by targeting multiple negative regulators of p27 in non-small cell lung cancer
MicroRNAs (miRNAs) control cell cycle progression by targeting the transcripts encoding for cyclins, CDKs and CDK inhibitors, such as p27(KIP1) (p27). p27 expression is controlled by multiple transcriptional and posttranscriptional mechanisms, including translational inhibition by miR-221/222 and po...
Kaydedildi:
Yayımlandı: | Oncogene |
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Asıl Yazarlar: | , , , , , , , , |
Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
2014
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4724947/ https://ncbi.nlm.nih.gov/pubmed/25151966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.267 |
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