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Homeodomain transcription factor and tumor suppressor Prep1 is required to maintain genomic stability
Prep1 is a homeodomain transcription factor that is essential in embryonic development and functions in the adult as a tumor suppressor. We show here that Prep1 is involved in maintaining genomic stability and preventing neoplastic transformation. Hypomorphic homozygous Prep1(i/i) fetal liver cells...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3141938/ https://ncbi.nlm.nih.gov/pubmed/21715654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105216108 |
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