Učitavanje...
Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome
Autocatalytic activation of an initiator caspase triggers the onset of apoptosis. In dying cells, caspase-9 activation is mediated by a multimeric adaptor complex known as the Apaf-1 apoptosome. The molecular mechanism by which caspase-9 is activated by the Apaf-1 apoptosome remains largely unknown....
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| Izdano u: | Proc Natl Acad Sci U S A |
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| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4246342/ https://ncbi.nlm.nih.gov/pubmed/25313070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1418000111 |
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