K-Ras(V14I) recapitulates Noonan syndrome in mice

Noonan syndrome (NS) is an autosomal dominant genetic disorder characterized by short stature, craniofacial dysmorphism, and congenital heart defects. NS also is associated with a risk for developing myeloproliferative disorders (MPD), including juvenile myelomonocytic leukemia (JMML). Mutations res...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Hernández-Porras, Isabel, Fabbiano, Salvatore, Schuhmacher, Alberto J., Aicher, Alexandra, Cañamero, Marta, Cámara, Juan Antonio, Cussó, Lorena, Desco, Manuel, Heeschen, Christopher, Mulero, Francisca, Bustelo, Xosé R., Guerra, Carmen, Barbacid, Mariano
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2014
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246321/
https://ncbi.nlm.nih.gov/pubmed/25359213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1418126111
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg