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Decreased polycystin 2 expression alters calcium-contraction coupling and changes β-adrenergic signaling pathways
Cardiac disorders are the main cause of mortality in autosomal-dominant polycystic kidney disease (ADPKD). However, how mutated polycystins predispose patients with ADPKD to cardiac pathologies before development of renal dysfunction is unknown. We investigate the effect of decreased levels of polyc...
Tallennettuna:
| Julkaisussa: | Proc Natl Acad Sci U S A |
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| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4246301/ https://ncbi.nlm.nih.gov/pubmed/25368166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415933111 |
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