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Decreased Polycystin 2 Levels Result in Non-Renal Cardiac Dysfunction with Aging
Mutations in the gene for polycystin 2 (Pkd2) lead to polycystic kidney disease, however the main cause of mortality in humans is cardiac related. We previously showed that 5 month old Pkd2+/- mice have altered calcium-contractile activity in cardiomyocytes, but have preserved cardiac function. Here...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4833351/ https://ncbi.nlm.nih.gov/pubmed/27081851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153632 |
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