A portable BRCA1-HAC (human artificial chromosome) module for analysis of BRCA1 tumor suppressor function

BRCA1 is involved in many disparate cellular functions, including DNA damage repair, cell-cycle checkpoint activation, gene transcriptional regulation, DNA replication, centrosome function and others. The majority of evidence strongly favors the maintenance of genomic integrity as a principal tumor...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Kononenko, Artem V., Bansal, Ruchi, Lee, Nicholas C.O., Grimes, Brenda R., Masumoto, Hiroshi, Earnshaw, William C., Larionov, Vladimir, Kouprina, Natalay
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Methods Online
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245969/
https://ncbi.nlm.nih.gov/pubmed/25260588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku870
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