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Amplicon rearrangements during the extrachromosomal and intrachromosomal amplification process in a glioma

The mechanisms of gene amplification in tumour cells are poorly understood and the relationship between extrachromosomal DNA molecules, named double minutes (dmins), and intrachromosomal homogeneously staining regions (hsr) is not documented at nucleotide resolution. Using fluorescent in situ hybrid...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Vogt, Nicolas, Gibaud, Anne, Lemoine, Frédéric, de la Grange, Pierre, Debatisse, Michelle, Malfoy, Bernard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245956/
https://ncbi.nlm.nih.gov/pubmed/25378339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1101
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