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Amplicon rearrangements during the extrachromosomal and intrachromosomal amplification process in a glioma

The mechanisms of gene amplification in tumour cells are poorly understood and the relationship between extrachromosomal DNA molecules, named double minutes (dmins), and intrachromosomal homogeneously staining regions (hsr) is not documented at nucleotide resolution. Using fluorescent in situ hybrid...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Vogt, Nicolas, Gibaud, Anne, Lemoine, Frédéric, de la Grange, Pierre, Debatisse, Michelle, Malfoy, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245956/
https://ncbi.nlm.nih.gov/pubmed/25378339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1101
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