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Relationships Linking Amplification Level to Gene Over-Expression in Gliomas

BACKGROUND: Gene amplification is thought to promote over-expression of genes favouring tumour development. Because amplified regions are usually megabase-long, amplification often concerns numerous syntenic or non-syntenic genes, among which only a subset is over-expressed. The rationale for these...

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Detalhes bibliográficos
Main Authors: Vogt, Nicolas, Gibaud, Anne, Almeida, Anna, Ourliac-Garnier, Isabelle, Debatisse, Michelle, Malfoy, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999539/
https://ncbi.nlm.nih.gov/pubmed/21170331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014249
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