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Molecular structure of double-minute chromosomes bearing amplified copies of the epidermal growth factor receptor gene in gliomas

Amplification of the epidermal growth factor receptor gene on double minutes is recurrently observed in cells of advanced gliomas, but the structure of these extrachromosomal circular DNA molecules and the mechanisms responsible for their formation are still poorly understood. By using quantitative...

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Bibliografski detalji
Glavni autori: Vogt, Nicolas, Lefèvre, Sandrine-Hélène, Apiou, Françoise, Dutrillaux, Anne-Marie, Cör, Andrej, Leuraud, Pascal, Poupon, Marie-France, Dutrillaux, Bernard, Debatisse, Michelle, Malfoy, Bernard
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC509208/
https://ncbi.nlm.nih.gov/pubmed/15269346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402979101
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