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Premature condensation induces breaks at the interface of early and late replicating chromosome bands bearing common fragile sites
Various studies suggest a tight relationship between chromosome rearrangements driving tumor progression and breaks at loci called common fragile sites. Most of these sites are induced after perturbation of the replication dynamics, notably by aphidicolin treatment. We have mapped the majority of th...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1312387/ https://ncbi.nlm.nih.gov/pubmed/16330769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506497102 |
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