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Polymerase η suppresses telomere defects induced by DNA damaging agents

Telomeres at chromosome ends are normally masked from proteins that signal and repair DNA double strand breaks (DSBs). Bulky DNA lesions can cause DSBs if they block DNA replication, unless they are bypassed by translesion (TLS) DNA polymerases. Here, we investigated roles for TLS polymerase η, (pol...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Pope-Varsalona, Hannah, Liu, Fu-Jun, Guzik, Lynda, Opresko, Patricia L.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245935/
https://ncbi.nlm.nih.gov/pubmed/25355508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1030
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