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Effectiveness of Spray Congealing to Obtain Physically Stabilized Amorphous Dispersions of a Poorly Soluble Thermosensitive API

An amorphous phase produced by micronization up to the molecular or colloidal level of a poorly soluble drug having low lipophilicity can distinctly enhance its solubility characteristics. However, though dispersing the molten mass of a poorly water-soluble drug within polymeric matrix has been foun...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:AAPS PharmSciTech
Main Authors: Kulthe, Viraj Vitthal, Chaudhari, Pravin Digambar
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245437/
https://ncbi.nlm.nih.gov/pubmed/24934386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0164-1
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