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Overcoming Poor Solubility of Dimenhydrinate: Development, Optimization and Evaluation of Fast Dissolving Oral Film

Purpose: To develop fast dissolving oral film to address vomiting and nausea in pediatric population. Methods: Oral films of Dimenhydrinate were prepared by solvent casting method by using hydroxypropylmethyl cellulose E5 (HPMC E5), polyethylene glycol 400 (PEG 400) and croscarmellose sodium. Solubi...

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Detalhes bibliográficos
Publicado no:Adv Pharm Bull
Main Authors: Jadhav, Yuvraj Govindrao, Galgatte, Upendra Chandrakant, Chaudhari, Pravin Digambar
Formato: Artigo
Idioma:Inglês
Publicado em: Tabriz University of Medical Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6311638/
https://ncbi.nlm.nih.gov/pubmed/30607345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2018.081
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