Nalaganje...

Relative Contributions of Solubility and Mobility to the Stability of Amorphous Solid Dispersions of Poorly Soluble Drugs: A Molecular Dynamics Simulation Study

Amorphous solid dispersions are considered a promising formulation strategy for the oral delivery of poorly soluble drugs. The limiting factor for the applicability of this approach is the physical (in)stability of the amorphous phase in solid samples. Minimizing the risk of reduced shelf life for a...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Pharmaceutics
Main Authors: Brunsteiner, Michael, Khinast, Johannes, Paudel, Amrit
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161151/
https://ncbi.nlm.nih.gov/pubmed/30037083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10030101
Oznake: Označite
Brez oznak, prvi označite!