Impairment of paravascular clearance pathways in the aging brain

OBJECTIVE: In the brain, protein waste removal is partly performed by paravascular pathways that facilitate convective exchange of water and soluble contents between cerebrospinal and interstitial fluids. Several lines of evidence suggest that bulk flow drainage via the glymphatic system is driven b...

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Pubblicato in:Ann Neurol
Autori principali: Kress, Benjamin T., Iliff, Jeffrey J., Xia, Maosheng, Wang, Minghuan, Wei, Helen, Zeppenfeld, Douglas, Xie, Lulu, Kang, Hongyi, Xu, Qiwu, Liew, Jason, Plog, Benjamin A., Ding, Fengfei, Deane, Rashid, Nedergaard, Maiken
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245362/
https://ncbi.nlm.nih.gov/pubmed/25204284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24271
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