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Impairment of paravascular clearance pathways in the aging brain

OBJECTIVE: In the brain, protein waste removal is partly performed by paravascular pathways that facilitate convective exchange of water and soluble contents between cerebrospinal and interstitial fluids. Several lines of evidence suggest that bulk flow drainage via the glymphatic system is driven b...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Kress, Benjamin T., Iliff, Jeffrey J., Xia, Maosheng, Wang, Minghuan, Wei, Helen, Zeppenfeld, Douglas, Xie, Lulu, Kang, Hongyi, Xu, Qiwu, Liew, Jason, Plog, Benjamin A., Ding, Fengfei, Deane, Rashid, Nedergaard, Maiken
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245362/
https://ncbi.nlm.nih.gov/pubmed/25204284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24271
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